Estimated glomerular filtration rate.
نویسندگان
چکیده
The recent article about estimated glomerular filtration rate (GFR) by Levey and colleagues (1) is remarkable. The authors suggest that the new equation may still have some bias and especially may have less precision in patients with GFRs greater than 60 mL/min per 1.73 m 2 . This is even more important if the GFR is greater than 90 mL/min per 1.73 m 2 . In the paper's Methods section, Levey and colleagues do not give the analytic coefficient of variation (CV) of their assays (Beckman Synchron CX3 [Global Medical Instrumentation, Inc., Ramsey, Minnesota] and Roche/Hitachi P module Creatinase Plus enzymatic assay [Roche Diagnostics, Basel, Switzerland]). This information is important especially for low or normal creatinine values. Indeed, the concept of critical difference is familiar to clinical biologists but should perhaps be reminded to internists.
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ورودعنوان ژورنال:
- Annals of internal medicine
دوره 146 1 شماره
صفحات -
تاریخ انتشار 2007